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MTN-035/DESIRE (Developing and Evaluating Short-acting Innovations for Rectal Use) – An acceptability, tolerability and adherence study of three placebo products for use in the rectum, including a douche, suppository and fast-dissolving rectal insert. The goal of the study is to help answer important questions about preferences for future rectal microbicide products. The products, which contain no active drugs, are being evaluated in 210 HIV-negative cisgender men, transgender men and transgender women who have sex with men at sites in Malawi, Peru, South Africa, Thailand and the U.S.  Results are expected in mid-2021.


What Do People Who Practice Anal Sex Desire for Preventing HIV?



MTN-035 Backgrounder


MTN-035 Q&A


See Also

MTN-035 Protocol


MTN-035 Study Page