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A Phase I safety study of the dapivirine vaginal ring in adolescent girls that was conducted at six U.S. research sites between August 2013 and July 2016 in collaboration with the National Institutes of Health-funded Adolescent Medicine Trials Network (ATN) for HIV/AIDS Interventions. The study was designed to collect data that regulatory bodies would require when considering whether to approve the dapivirine ring for HIV prevention. As such, MTN-023/IPM 030 is part of a package of studies, with ASPIRE and The Ring Study as the centerpiece, that IPM, as the ring’s developer and regulatory sponsor, plans to submit for regulatory review. Results from MTN-023/IPM 30 were presented at IAS 2017.


Researchers present additional evidence on the safety of the dapivirine vaginal ring

for HIV prevention in women



Dapivirine ring studies in adolescent girls and young women - Q&A



HIV prevention dapivirine vaginal ring found safe and acceptable in US adolescent girls



See Also

MTN-023/IPM 030 Protocol


MTN-023/IPM 030 Study Page


About the REACH Study (MTN-034)