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The first study of its kind involving the dapivirine vaginal ring, MTN-029/IPM 039 will determine whether drug released from the dapivirine ring into the vagina gets absorbed by breastmilk. Approximately 16 women who are no longer breastfeeding but are still producing breast milk will be enrolled and use the ring for 14 consecutive days. Its results may support future studies involving both breastfeeding mothers and their infants. The study, which began in March 2016, was conducted at two U.S.-based clinical research sites.


Researchers present additional evidence on the safety of the dapivirine vaginal ring for HIV prevention in women



U.S. study of dapivirine ring in lactating women finds little drug gets into breast milk



See Also

MTN-029/IPM 039 Protocol


MTN-029/IPM 039 Study Page


HOPE and Beyond: Next steps and planned studies of the dapivirine vaginal ring