Microbicide Trials Network

MTN-009, or the HIV Drug Resistance Study, is a cross-sectional study to determine if women who are found to be HIV-positive during pre-screening or screening for an HIV prevention trial have evidence of drug resistant virus. This study also aims to understand the possible risk factors that contribute to drug resistance.

With increasingly greater access to ARVs for treatment in sub-Saharan Africa and the potential that ARV-based prevention methods will be introduced in the future, it will be important to understand how tandem ARV-based treatment and prevention strategies might impact individual responses to either interventional and public health programs more broadly. By understanding the current status of HIV resistance in newly diagnosed HIV positive women of reproductive age, researchers will be able to make more informed decisions concerning future ARV-based prevention trials that target the female population. Approximately 350 HIV-infected women will be enrolled in MTN-009.